Atropine / Chlorpheniramine
Atropine/Chlorpheniramine is a combination medication that pairs an anticholinergic agent (atropine) with a first-generation antihistamine (chlorpheniramine). This combination is used to address allergy symptoms and related conditions by reducing allergic responses while also decreasing secretions. The anticholinergic component helps dry excessive secretions, while the antihistamine provides relief from histamine-mediated symptoms such as sneezing, runny nose, and itchy eyes.
A combination antihistamine and anticholinergic used for allergic conditions with drying effects on secretions.
Key facts at a glance
- RxNorm
- 689595
- Generic
- Atropine / Chlorpheniramine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for symptomatic relief of allergic conditions including allergic rhinitis and hay fever, as well as cold symptoms. May also be employed for pre-operative medication to reduce secretions during anesthesia.
Chlorpheniramine blocks H1 histamine receptors, preventing allergic responses like sneezing and itching. Atropine blocks muscarinic receptors, reducing secretions and providing anticholinergic effects that complement the antihistamine action.
May cause drowsiness, dry mouth, blurred vision, and urinary retention. Use with caution in elderly patients, those with glaucoma, benign prostatic hyperplasia, or cardiac conditions. Avoid alcohol and operating machinery until you know how this medication affects you. Should not be used in newborns or premature infants.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy