Atropine / Chlorpheniramine / Phenylephrine / Phenyltoloxamine
This combination medication contains four active ingredients that work together to relieve multiple symptoms of colds, allergies, and respiratory infections. It provides relief from nasal congestion, sneezing, runny nose, itchy eyes, and excess mucus production. The combination of antihistamines with a decongestant and anticholinergic agent makes it suitable for treating complex upper respiratory symptoms.
A multi-symptom cold and allergy relief medication combining antihistamines, decongestant, and anticholinergic agents.
Key facts at a glance
- RxNorm
- 689598
- Generic
- Atropine / Chlorpheniramine / Phenylephrine / Phenyltoloxamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of common cold symptoms, allergic rhinitis, hay fever, and sinus congestion including runny nose, sneezing, itchy/watery eyes, nasal congestion, and postnasal drip. May also be used for upper respiratory allergies.
Chlorpheniramine and phenyltoloxamine are first-generation antihistamines that block histamine receptors to reduce allergic symptoms. Phenylephrine is a nasal decongestant that constricts blood vessels in the nasal passages to reduce swelling and congestion. Atropine is an anticholinergic that reduces secretions and drying effects.
May cause drowsiness; avoid operating machinery or driving until you know how this medication affects you. Do not use if you have certain conditions including glaucoma, prostate enlargement, or urinary retention without consulting a doctor. Avoid alcohol and other sedating medications while taking this product. Not recommended for children under certain ages without medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy