Atropine / Hydrocortisone
Atropine/Hydrocortisone is an ophthalmic combination medication pairing an anticholinergic agent with a corticosteroid. This combination is primarily used to treat inflammatory eye conditions while preventing complications like iris adhesions. The atropine component keeps the pupil dilated while hydrocortisone reduces inflammation in the eye.
An eye medication combining a dilating agent with an anti-inflammatory steroid to treat uveitis and related inflammatory eye conditions.
Key facts at a glance
- RxNorm
- 1008192
- Generic
- Atropine / Hydrocortisone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of anterior uveitis, iritis, and other inflammatory conditions of the eye. Also used post-operatively following ocular surgery to reduce inflammation and prevent formation of synechiae (adhesions between the iris and lens/cornea). May be prescribed for certain corneal conditions and episcleritis.
Hydrocortisone is a corticosteroid that works by suppressing the inflammatory response through inhibition of prostaglandin synthesis and reduction of inflammatory cell activity. Atropine is an anticholinergic that blocks muscarinic receptors in the eye, causing pupil dilation (mydriasis) and paralysis of the ciliary muscle (cycloplegia), which helps relieve pain and prevents the iris from sticking to surrounding structures.
For ophthalmic use only; avoid contamination of the dropper tip. May cause temporary blurred vision and sensitivity to light. Use with caution in patients with glaucoma, as pupil dilation can increase intraocular pressure. Systemic absorption is minimal but possible. Do not discontinue abruptly after prolonged use. Contact lens wear should typically be avoided during treatment unless directed by a physician.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy