Atropine / Hydromorphone
Atropine/Hydromorphone is a combination medication that pairs an anticholinergic agent with an opioid analgesic. This combination is used in certain clinical settings where both antisialagogue effects (reducing excessive secretions) and opioid analgesia are desired.
A combination medication providing both antisecretory and analgesic effects for specific clinical situations.
Key facts at a glance
- RxNorm
- 1007561
- Generic
- Atropine / Hydromorphone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
May be used as preoperative medication to reduce salivation and provide baseline analgesia, and in certain acute or procedural pain management situations where both antisecretory and analgesic effects are beneficial.
Atropine blocks muscarinic acetylcholine receptors to reduce salivary and respiratory secretions, while hydromorphone binds to mu-opioid receptors to produce analgesia and sedation.
Use requires medical supervision due to opioid-related risks including respiratory depression and dependence; anticholinergic effects may cause dry mouth, blurred vision, and urinary retention; contraindicated in patients with certain cardiac, gastrointestinal, or urinary conditions. Dosage must be individualized and carefully titrated.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy