Atropine / Hyoscyamine / Methenamine / Phenyl Salicylate
This combination medication treats urinary tract infections and associated symptoms by combining four agents that work together to address infection, bladder spasms, and pain. The anticholinergic components (atropine and hyoscyamine) relax urinary tract smooth muscle, while methenamine acts as a urinary antiseptic and phenyl salicylate provides analgesic and mild antiseptic effects.
A combination urinary medication for treating UTIs and bladder symptoms by reducing spasms, fighting bacteria, and relieving pain.
Key facts at a glance
- RxNorm
- 1008128
- Generic
- Atropine / Hyoscyamine / Methenamine / Phenyl Salicylate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of urinary tract infections, cystitis, bladder spasms, and associated symptoms such as dysuria (painful urination), urinary frequency, and bladder discomfort.
Hyoscyamine and atropine provide antispasmodic effects by blocking acetylcholine receptors; methenamine converts to formaldehyde in acidic urine to kill urinary pathogens; phenyl salicylate offers mild analgesic and antiseptic properties in the urinary tract.
Requires acidic urine (pH below 6) for optimal methenamine effectiveness; common side effects include dry mouth, constipation, blurred vision, and drowsiness; contraindicated in glaucoma, urinary obstruction, or myasthenia gravis; patients should stay well hydrated.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy