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Atropine / Hyoscyamine / Phenylephrine / Pseudoephedrine / Scopolamine

Published: July 27, 2026Updated: August 27, 2026

This combination medication contains both anticholinergic agents (atropine, hyoscyamine, scopolamine) and decongestants (phenylephrine, pseudoephedrine), making it useful for managing multiple symptoms associated with upper respiratory infections and sinus congestion. The anticholinergic components help reduce spasms, cramping, and excessive secretions, while the decongestants work to relieve nasal and sinus congestion. This multi-ingredient formulation is typically used for symptomatic relief in patients experiencing concurrent respiratory and gastrointestinal discomfort.

Quick summary

A combination of anticholinergics and decongestants used to relieve congestion, spasms, and other cold/allergy symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1007162
Generic
Atropine / Hyoscyamine / Phenylephrine / Pseudoephedrine / Scopolamine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for symptomatic relief of upper respiratory conditions including nasal congestion, sinus pressure, and associated discomfort. May also help manage accompanying gastrointestinal symptoms such as cramping and spasms.

The anticholinergic ingredients (atropine, hyoscyamine, scopolamine) block acetylcholine receptors, reducing smooth muscle spasms, secretions, and cramping. The decongestant ingredients (phenylephrine, pseudoephedrine) constrict blood vessels in the nasal passages, reducing swelling and congestion.

Due to multiple anticholinergic effects, this medication may cause dry mouth, blurred vision, drowsiness, or urinary retention. Caution is advised in patients with glaucoma, prostate enlargement, or heart conditions. Should be avoided in children and elderly patients due to sensitivity to anticholinergic effects. May interact with other medications; consult a healthcare provider before use.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy