Atropine / Morphine
Atropine/Morphine is a combination medication pairing an opioid analgesic with an anticholinergic agent. It is used primarily for preoperative sedation and analgesia, as well as for management of pain associated with smooth muscle spasms. The combination allows morphine to provide pain relief while atropine reduces secretions and prevents opioid-induced bradycardia.
A combination opioid-anticholinergic used for preoperative preparation and pain management with smooth muscle spasms.
Key facts at a glance
- RxNorm
- 689610
- Generic
- Atropine / Morphine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Preoperative medication to provide sedation, reduce secretions, and prevent bradycardia; management of moderate to severe pain when accompanied by smooth muscle spasms; certain emergency situations requiring both analgesia and reduced respiratory secretions.
Morphine binds to opioid receptors in the central nervous system to alter pain perception and produce analgesia. Atropine is an anticholinergic that blocks muscarinic receptors, reducing secretions and preventing bradycardia while also providing antispasmodic effects on smooth muscle.
This is a controlled substance due to the morphine component. Side effects may include respiratory depression, sedation, dry mouth, constipation, and tachycardia. Use requires medical supervision; may interact with other CNS depressants. Not recommended for long-term use due to addiction potential and anticholinergic effects.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy