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Attapulgite / Morphine

Published: July 27, 2026Updated: August 27, 2026

Attapulgite/Morphine is a combination medication pairing an anti-diarrheal adsorbent with an opioid pain reliever. This multi-ingredient product addresses both the gastrointestinal symptoms and associated abdominal discomfort of acute diarrhea. It is typically reserved for cases where diarrhea is accompanied by significant cramping or pain requiring analgesic relief.

Quick summary

A combination anti-diarrheal and pain medication used when diarrhea causes significant discomfort requiring both symptom and pain management.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
1007383
Generic
Attapulgite / Morphine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of acute diarrhea and the abdominal cramping/pain associated with it, particularly when over-the-counter anti-diarrheals alone prove insufficient for symptom control.

Attapulgite is a naturally occurring clay that adsorbs water, bacteria, and toxins in the gastrointestinal tract to firm stools and reduce fluid loss. Morphine is an opioid agonist that binds to mu-opioid receptors in the gut and central nervous system, reducing intestinal motility and alleviating pain signals.

Due to the morphine component, this medication carries risks associated with opioid use including drowsiness, constipation, and potential for dependence. It should not be used in certain gastrointestinal conditions (such as suspected toxic megacolon) or combined with other CNS depressants without medical supervision. Patients should be advised against operating machinery and should use only as prescribed. This is a prescription-only medication in most jurisdictions.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy