Avatrombopag Maleate
Avatrombopag Maleate is an oral thrombopoietin receptor agonist that stimulates platelet production in the bone marrow. It is used to treat thrombocytopenia (low platelet counts) in adults with chronic liver disease who require procedures, and in patients with chronic immune thrombocytopenia who have not responded adequately to other treatments.
Avatrombopag Maleate is a medication that raises platelet counts by stimulating the thrombopoietin receptor, used for thrombocytopenia associated with liver disease or immune thrombocytopenia.
Key facts at a glance
- RxNorm
- 2045727
- Generic
- Avatrombopag Maleate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of thrombocytopenia in adult patients with chronic liver disease who are scheduled to undergo a medical procedure, and treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous therapy.
Avatrombopag Maleate is a thrombopoietin receptor agonist that binds to and activates the thrombopoietin receptor on megakaryocyte progenitor cells in the bone marrow, stimulating their proliferation and differentiation, which leads to increased platelet production.
May increase the risk of thrombotic events; should not be used to normalize platelet counts. Can cause hepatotoxicity; liver function monitoring recommended. Should be taken with food. Contraindicated in patients with known hypersensitivity to the drug.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy