Norethindrone
Aygestin is a synthetic progestin medication that contains norethindrone acetate. It is primarily used to treat endometriosis, menstrual disorders such as amenorrhea and abnormal uterine bleeding, and as part of hormone replacement therapy in postmenopausal women. The medication works by mimicking the effects of naturally occurring progesterone in the body.
Aygestin is a progestin medication used to treat endometriosis, menstrual disorders, and hormone-related conditions by mimicking progesterone activity.
Key facts at a glance
- RxNorm
- 215496
- Generic
- Aygestin
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Aygestin is used to treat endometriosis, amenorrhea (absence of menstruation), and abnormal uterine bleeding. It may also be used as a component of hormone replacement therapy for postmenopausal women and to support pregnancy in women with progesterone deficiency.
Aygestin contains norethindrone acetate, a synthetic form of progesterone that binds to progesterone receptors in the body. It helps regulate the menstrual cycle, inhibits estrogen's effects on endometrial tissue, and supports the uterine lining when needed.
Aygestin is contraindicated in patients with known or suspected pregnancy, liver disease, or history of blood clots or stroke. Common side effects may include breakthrough bleeding, mood changes, headache, and breast tenderness. Patients should be monitored for signs of depression or thromboembolic events while taking this medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy