Aztreonam
Azactam (aztreonam) is a monobactam antibiotic used to treat serious gram-negative bacterial infections, including urinary tract infections, lower respiratory tract infections, septicemia, and intra-abdominal infections. It is often prescribed for patients who have allergies to penicillins or cephalosporins, as it has a low risk of cross-reactivity with beta-lactam antibiotics.
Azactam is an injectable antibiotic used to treat serious gram-negative bacterial infections in patients who may be allergic to other common antibiotics.
Key facts at a glance
- RxNorm
- 202561
- Generic
- Azactam
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Azactam is used to treat infections caused by susceptible gram-negative bacteria, including urinary tract infections, lower respiratory tract infections (such as pneumonia), septicemia, skin and soft tissue infections, intra-abdominal infections, and gonorrhea. It may be used in combination with other antibiotics for polymicrobial infections.
Azactam is a monobactam antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs) within the bacterial cell wall, disrupting cell wall construction and leading to bacterial cell death. It is particularly effective against aerobic gram-negative bacteria.
Azactam is administered intravenously or intramuscularly by a healthcare professional. It should be used with caution in patients with kidney or liver impairment. Common side effects may include injection site reactions, rash, and gastrointestinal symptoms. While it can be used in penicillin-allergic patients, rare allergic reactions are still possible. Full course of treatment should be completed as prescribed.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy