Azatadine
Azatadine is a second-generation antihistamine used to relieve symptoms of allergic conditions such as seasonal allergic rhinitis and chronic urticaria. It works by blocking histamine H1 receptors, reducing allergic symptoms like sneezing, itching, and runny nose. This medication has been available in oral form and is typically used in adults and children.
Azatadine is an antihistamine used to treat allergic rhinitis and other allergic reactions.
Key facts at a glance
- ATC
- R06AX09
- RxNorm
- 18600
- Generic
- Azatadine
- Class
- atc-r06
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks, use only if clearly necessary
regular prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second trimesteravoid if possible
use only if benefits outweigh potential risks
regular prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteravoid if possible
avoid close to delivery due to potential effects on newborn
fetal monitoring in late pregnancy
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse with caution
azatadine may pass into breast milk, use alternative antihistamines with better safety data or discontinue breastfeeding
monitor infant for excessive drowsiness
Use with caution and monitor for adverse effects.
geriatric
elderlyreduce dose, start with lowest effective dose
use with caution due to increased sensitivity to anticholinergic effects, increased risk of sedation and cognitive impairment
monitor for sedation, confusion, anticholinergic effects
Use with caution and monitor for adverse effects.
pediatric_age
children under 12not recommended for children under 12 years
safety and efficacy not established in children under 12, use alternative antihistamines with pediatric dosing data
monitor for paradoxical excitement or sedation
Use with caution and monitor for adverse effects.
renal_impairment
mild to moderatereduce dose by 25-50%
use with caution, dose adjustment recommended based on creatinine clearance
monitor renal function periodically
Use with caution and monitor for adverse effects.
renal_impairment
severeavoid or use significantly reduced dose
not recommended in severe renal impairment unless benefits outweigh risks
close monitoring of renal function and drug levels
Use of this medication in this population requires careful consideration of risks and benefits.
hepatic_impairment
mild to moderatereduce dose by 25-50%
use with caution, dose adjustment may be needed due to altered metabolism
monitor liver function tests
Use with caution and monitor for adverse effects.
hepatic_impairment
severeavoid or use significantly reduced dose
use with extreme caution in severe hepatic impairment
monitor liver function and for signs of toxicity
Use with caution and monitor for adverse effects.
alcohol_users
concurrent alcohol useavoid concomitant use
avoid alcohol while taking azatadine due to enhanced sedative effects
monitor for excessive sedation and impaired coordination
Use of this medication in this population requires careful consideration of risks and benefits.
Statistics and clinical data
Commonly prescribed since
No prescribing data available for this compound
Drug class
No classification data available
Common uses
No therapeutic use data available
Regulatory approval
No FDA-approved drug named Azatadine found in database
Treatment of seasonal and perennial allergic rhinitis (hay fever), allergic conjunctivitis, chronic urticaria (hives), and other allergic skin conditions characterized by itching and rash.
Azatadine is a selective histamine H1 receptor antagonist that blocks the action of histamine, a substance released during allergic reactions. By preventing histamine from binding to its receptors, it reduces allergic symptoms including sneezing, itching, nasal discharge, and skin reactions.
May cause drowsiness, dry mouth, and blurred vision. Use with caution in patients with glaucoma, urinary retention, or thyroid disorders. Avoid alcohol and CNS depressants while taking this medication. Consult healthcare provider before use if pregnant, breastfeeding, or giving to children.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy