Bacitracin / Neomycin / Polymyxin B
Bacitracin/Neomycin/Polymyxin B is a topical combination antibiotic used to treat and prevent bacterial infections, particularly of the skin and eyes. This three-antibiotic formulation provides broad-spectrum coverage against many common gram-positive and gram-negative bacteria. It is typically applied directly to the affected area to treat minor wounds, burns, or eye infections.
A broad-spectrum topical antibiotic combination used to treat and prevent bacterial infections of the skin and eyes.
Key facts at a glance
- RxNorm
- 477619
- Generic
- Bacitracin / Neomycin / Polymyxin B
- Class
- multi-ingredient
- Brands
- Neo-Polycin
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats and prevents minor bacterial skin infections, including cuts, scrapes, burns, and post-surgical wounds. Also used for superficial eye infections (blepharitis, conjunctivitis) and to prevent infection after minor eye procedures.
Three antibiotics work together: Bacitracin inhibits bacterial cell wall synthesis, Neomycin disrupts bacterial protein production, and Polymyxin B damages bacterial cell membranes. Together, they provide synergistic broad-spectrum coverage against gram-positive and gram-negative bacteria.
For topical use only. Avoid contact with eyes unless directed for ophthalmic use. Do not use on deep wounds, animal bites, or large areas of burned skin. Allergic reactions to neomycin are possible. Long-term use may lead to bacterial resistance or sensitization. Discontinue use if rash, irritation, or worsening symptoms occur.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy