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Mupirocin

Published: July 26, 2026Updated: September 3, 2026

Bactroban is a topical antibiotic medication used to treat bacterial skin infections such as impetigo, folliculitis, and other minor skin infections caused by susceptible bacteria. It is also available as a nasal ointment for eliminating nasal carriage of Staphylococcus aureus.

Quick summary

Topical antibiotic for bacterial skin infections and nasal carriage of staph bacteria.

Medically reviewed by WellAlly Editorial TeamLast reviewed September 3, 2026Editorial policy

Key facts at a glance

RxNorm
227591
Generic
Bactroban
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of primary skin infections including impetigo, folliculitis, and ecthyma caused by susceptible bacteria. Also indicated for elimination of nasal carriage of Staphylococcus aureus (including MRSA) in adults and healthcare workers.

Mupirocin works by inhibiting bacterial protein synthesis through reversible binding to bacterial isoleucyl-tRNA synthetase, preventing the incorporation of isoleucine into growing polypeptide chains. This bacteriostatic action is effective against gram-positive bacteria including Staphylococcus aureus and Streptococcus pyogenes.

For topical use only; avoid contact with eyes and mucous membranes. Apply a small amount to affected area 2-3 times daily for up to 10 days. Not for prolonged use due to risk of bacterial resistance. The nasal ointment is applied inside the nostrils twice daily. Allergic reactions and local skin irritation may occur.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy