Bamifylline Hydrochloride
Bamifylline Hydrochloride is a xanthine derivative bronchodilator used primarily in the treatment of asthma and other respiratory conditions involving bronchospasm. It works by relaxing the smooth muscles of the airways, making it easier to breathe. This medication is typically prescribed when standard asthma treatments need additional support.
A bronchodilator medication used to treat asthma and respiratory conditions by relaxing airway muscles.
Key facts at a glance
- RxNorm
- 236152
- Generic
- Bamifylline Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse lowest effective dose
use only if clearly needed
fetal growth monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse lowest effective dose
avoid near term due to risk of uterine irritability
fetal monitoring and uterine activity
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse with caution
bamifylline is excreted in breast milk; monitor infant for irritability or feeding problems
monitor infant for adverse effects
Use with caution and monitor for adverse effects.
geriatric
elderlyreduce dose by 25-50%
start with lowest dose; monitor for cardiovascular and CNS effects
regular monitoring of heart rate, blood pressure, and CNS effects
Use with caution and monitor for adverse effects.
pediatric_age
children under 12use with extreme caution; weight-based dosing
not recommended for children under 6 years; use only under close medical supervision
closely monitor for adverse effects
Use with caution and monitor for adverse effects.
renal_impairment
mild to moderatereduce dose by 25-50%
adjust dose based on renal function; monitor serum levels if available
monitor renal function and drug levels
Use with caution and monitor for adverse effects.
hepatic_impairment
moderate to severereduce dose by 50% or avoid
use with extreme caution; metabolism may be impaired
monitor liver function tests and drug levels
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information
Common uses
Common therapeutic uses
Treatment of asthma, bronchial asthma, and bronchospasm associated with obstructive airway diseases. May be used as adjunctive therapy when standard treatments are insufficient.
As a xanthine derivative, it acts as a phosphodiesterase inhibitor, leading to increased levels of cyclic AMP in bronchial smooth muscle cells, which results in bronchodilation. May also have some anti-inflammatory properties.
May interact with other xanthine derivatives, certain antibiotics, and cardiovascular medications. Common side effects may include gastrointestinal discomfort, headache, and tachycardia. Dosage must be individualized and therapeutic drug monitoring may be required. Contraindicated in patients with active peptic ulcers and certain cardiac conditions.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy