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Bamipine Lactate

Published: July 26, 2026Updated: August 24, 2026

Bamipine Lactate is a first-generation antihistamine medication used primarily for the treatment of allergic conditions. As an H1 receptor antagonist, it works by blocking histamine effects in the body. This medication is typically prescribed for allergic reactions including hay fever, urticaria, and other hypersensitivity disorders.

Quick summary

Bamipine Lactate is an antihistamine used to treat allergic conditions by blocking H1 histamine receptors.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

RxNorm
236530
Generic
Bamipine Lactate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
500mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
250mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
400mg daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose that may cause serious toxicity
Chronic overdose: Prolonged use leading to accumulation and increased risk of adverse effects
Immediate actions
Gastric lavage within 1-2 hours of ingestion, activated charcoal, supportive care
Antidote
No specific antidote available(Treatment is supportive and symptomatic; no specific antidote reverses antihistamine toxicity)
Poison Control: 1-800-222-1222

Special Populations

8 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

use only if benefits outweigh potential risks to fetus

Monitor

regular prenatal checkups

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

avoid close to delivery

Key Recommendations

avoid use near term due to potential effects on fetus

Monitor

fetal monitoring in late pregnancy

Use with caution and monitor for adverse effects.

⚠

lactation

breastfeeding
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

avoid or discontinue breastfeeding during treatment

Monitor

monitor infant for excessive drowsiness

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly
caution
FDA Category
N
Dose Adjustment

reduce dose

Key Recommendations

start with lowest dose, monitor for sedation and anticholinergic effects

Monitor

monitor for dizziness, falls, cognitive impairment

Use with caution and monitor for adverse effects.

⚠

pediatric_age

children under 12
caution
FDA Category
C
Dose Adjustment

weight-based dosing

Key Recommendations

use under medical supervision, avoid in very young children

Monitor

monitor for paradoxical excitation

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild
caution
FDA Category
N
Dose Adjustment

no adjustment needed

Key Recommendations

monitor renal function periodically

Monitor

check creatinine clearance

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe
caution
FDA Category
N
Dose Adjustment

reduce dose by 50%

Key Recommendations

use with caution, consider extended dosing intervals

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

moderate to severe
caution
FDA Category
N
Dose Adjustment

reduce dose

Key Recommendations

use with caution due to reduced metabolism

Monitor

monitor liver function tests

Use with caution and monitor for adverse effects.

Statistics and clinical data

drug_classWHO
2023

Drug class

Value:First-generation H1 antihistamine

Antihistamine medication classification

usageMedical guidelines
2023

Common uses

Value:Allergic rhinitis, urticaria, pruritus

Therapeutic indications

mechanism pharmacology databases
2023

Mechanism of action

Value:H1 receptor antagonist

Primary pharmacological mechanism

Treatment of allergic conditions such as hay fever (seasonal allergic rhinitis), urticaria (hives), pruritus (itching), and other hypersensitivity reactions. May also be used for allergic skin conditions and as adjunctive therapy in anaphylactic reactions.

Bamipine Lactate is a piperidine-derived H1 receptor antagonist that competitively blocks histamine at H1 receptor sites, preventing histamine-mediated allergic symptoms including itching, swelling, and vasodilation.

First-generation antihistamines may cause drowsiness. Use with caution in patients with glaucoma, urinary retention, or cardiovascular conditions. Avoid alcohol and CNS depressants while taking this medication. Consult healthcare provider before use during pregnancy or breastfeeding.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy