Belantamab Mafodotin
Belantamab mafodotin-blmf is a targeted therapy medication known as an antibody-drug conjugate used to treat certain cancers. It is primarily used for adults with relapsed or refractory multiple myeloma who have received prior treatments. The medication works by delivering a cytotoxic agent directly to cancer cells that express a specific protein marker.
Belantamab mafodotin-blmf is a BCMA-directed antibody-drug conjugate used for relapsed or refractory multiple myeloma after prior therapies.
Key facts at a glance
- RxNorm
- 2387833
- Generic
- Belantamab Mafodotin-Blmf
- Class
- pin-variant
- Brands
- Blenrep
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior therapies, including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulatory agent.
This medication is a B-cell maturation antigen (BCMA)-directed antibody-drug conjugate. It binds to BCMA on the surface of cancer cells and delivers a cytotoxic agent (monomethyl auristatin F) that induces cell death.
Common side effects include keratopathy (eye-related changes), thrombocytopenia, anemia, infusion-related reactions, and vision changes. Regular eye examinations are recommended during treatment. Use with caution in patients with moderate-to-severe hepatic impairment. Pregnancy should be avoided during treatment due to potential harm to the fetus.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy