Panobinostat
Beleodaq (belinostat) is a histone deacetylase (HDAC) inhibitor used to treat adults with relapsed or refractory peripheral T-cell lymphoma (PTCL) after at least one prior therapy. It is administered as an intravenous infusion and works by targeting cancer cells through enzyme inhibition.
Beleodaq is an IV chemotherapy drug for relapsed peripheral T-cell lymphoma that works by inhibiting histone deacetylase enzymes.
Key facts at a glance
- RxNorm
- 1543548
- Generic
- Beleodaq
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Beleodaq is indicated for the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL) in adult patients who have received at least one prior systemic therapy. It is used when the cancer has returned or did not respond to previous treatments.
Beleodaq is a histone deacetylase (HDAC) inhibitor. It works by blocking HDAC enzymes, which leads to accumulation of acetylated histones and other proteins. This causes cell cycle arrest and apoptosis (programmed cell death), particularly in malignant T-cells.
Beleodaq carries risks including serious side effects such as tumor lysis syndrome, myelosuppression (low blood counts), hepatotoxicity, and infections. Common side effects include nausea, fatigue, fever, and anemia. Treatment should be supervised by oncologists experienced in chemotherapy, with regular monitoring of blood counts and liver function. It is administered as an IV infusion over 30-60 minutes on days 1-5 of a 21-day cycle.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy