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Belladonna Alkaloids / Chlorpheniramine / Phenylephrine / Phenylpropanolamine

Published: July 27, 2026Updated: August 28, 2026

This combination medication contains four active ingredients that work together to relieve symptoms of the common cold, allergies, and sinus congestion. Belladonna alkaloids provide anticholinergic effects to reduce excessive respiratory secretions and relax smooth muscles, while chlorpheniramine acts as an antihistamine to address sneezing, runny nose, and itchy eyes. Phenylephrine and phenylpropanolamine function as decongestants by constricting blood vessels in the nasal passages, thereby decreasing swelling and congestion.

Quick summary

A multi-symptom cold and allergy medication combining anticholinergic, antihistamine, and decongestant properties to address congestion, allergic symptoms, and excessive secretions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1007644
Generic
Belladonna Alkaloids / Chlorpheniramine / Phenylephrine / Phenylpropanolamine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporary relief of nasal congestion, sinus pressure, sneezing, runny nose, itchy nose or throat, and other upper respiratory symptoms associated with colds, allergies, or sinusitis

Belladonna alkaloids reduce respiratory secretions through anticholinergic action; chlorpheniramine blocks histamine to relieve allergic symptoms; phenylephrine and phenylpropanolamine constrict blood vessels in nasal passages to reduce swelling and congestion

May cause drowsiness or dizziness. Avoid alcohol and operating machinery. Not recommended for patients with certain conditions including narrow-angle glaucoma, urinary retention, or cardiovascular disease. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy