Belladonna Alkaloids / Opium
Belladonna Alkaloids/Opium is a combination medication containing anticholinergic belladonna alkaloids and opium alkaloids. It is primarily used to treat severe diarrhea and abdominal cramps by reducing intestinal spasms and motility. This medication is typically prescribed when other anti-diarrheal treatments have been ineffective.
A combination anticholinergic/opioid medication used to treat severe diarrhea and abdominal cramping by relaxing intestinal smooth muscle.
Key facts at a glance
- RxNorm
- 215597
- Generic
- Belladonna Alkaloids / Opium
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of severe diarrhea, including functional GI disorders with diarrhea, and associated abdominal cramping and pain. May also be used for symptomatic relief of bladder spasms.
Belladonna alkaloids (atropine, scopolamine) block acetylcholine receptors in smooth muscle, reducing spasms and secretions. Opium alkaloids (morphine, codeine) act on opioid receptors in the gut, slowing intestinal motility and reducing diarrhea.
Contains controlled substances; use carries risk of dependence with prolonged use. Anticholinergic effects include dry mouth, constipation, blurred vision, and urinary retention. May cause drowsiness; avoid alcohol and operating machinery. Contraindicated in glaucoma, urinary obstruction, and severe hepatic disease. Use cautiously in elderly patients due to anticholinergic effects. Not recommended for long-term use.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy