Belladonna Alkaloids / Simethicone
Belladonna Alkaloids/Simethicone is a combination medication used to treat abdominal pain, cramping, and bloating associated with irritable bowel syndrome (IBS) and other functional gastrointestinal disorders. It combines an anticholinergic agent that relaxes smooth muscle in the digestive tract with an anti-foaming agent that helps relieve gas and bloating by breaking up trapped gas bubbles.
A combination medication for IBS-related abdominal cramps and bloating that relaxes intestinal muscles and helps expel gas.
Key facts at a glance
- RxNorm
- 1008938
- Generic
- Belladonna Alkaloids / Simethicone
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats irritable bowel syndrome (IBS), functional gastrointestinal disorders, and symptoms including abdominal cramping, pain, bloating, and excessive gas caused by smooth muscle spasms in the digestive tract.
Belladonna alkaloids block acetylcholine receptors in the digestive tract, reducing smooth muscle spasms and intestinal secretions. Simethicone is an anti-foaming agent that changes the surface tension of gas bubbles, allowing them to combine and be expelled more easily.
Common side effects include dry mouth, blurred vision, constipation, and urinary retention due to anticholinergic effects. Should be avoided in patients with glaucoma, urinary retention, or gastrointestinal obstruction. Use with caution in elderly patients. May interact with other anticholinergic medications. Not recommended for long-term use without medical supervision.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy