Belladonna Extract, USP / Opium
Belladonna Extract USP/Opium is a combination medication used to treat gastrointestinal disorders characterized by pain and spasms. Belladonna provides anticholinergic effects to reduce intestinal spasms and secretions, while opium adds analgesic properties. This medication is typically prescribed for conditions like irritable bowel syndrome and intestinal colic.
A combination of belladonna and opium used to relieve painful intestinal spasms and cramping.
Key facts at a glance
- RxNorm
- 1008288
- Generic
- Belladonna Extract, Usp / Opium
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to treat gastrointestinal conditions involving smooth muscle spasms, including irritable bowel syndrome, intestinal colic, peptic ulcers, and other conditions causing abdominal cramping and pain.
Belladonna extract contains anticholinergic alkaloids (primarily atropine and scopolamine) that block acetylcholine receptors, reducing intestinal motility and secretions. Opium contains opioid alkaloids that act on mu-opioid receptors in the GI tract, providing analgesic effects and further reducing intestinal activity.
May cause dry mouth, blurred vision, constipation, and drowsiness. Should be used with caution in elderly patients and those with urinary retention, glaucoma, or benign prostatic hyperplasia. Risk of dependence exists due to the opium component. Avoid alcohol and other CNS depressants while taking this medication.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy