Belladonna Extract, USP / Phenobarbital
Belladonna Extract/Phenobarbital is a combination medication used primarily for gastrointestinal disorders characterized by spasms, excessive secretions, and pain, such as peptic ulcers and irritable bowel syndrome. The belladonna component provides anticholinergic effects to reduce GI motility and secretions, while phenobarbital acts as a sedative to help relax the patient. This medication is typically prescribed when conservative treatments have been unsuccessful.
A combination anticholinergic and sedative medication used for spastic gastrointestinal conditions.
Key facts at a glance
- RxNorm
- 1008045
- Generic
- Belladonna Extract, Usp / Phenobarbital
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for peptic ulcer disease and irritable bowel syndrome to reduce gastric secretions, GI spasms, and associated anxiety. Also used for other functional GI disorders with spastic components.
Belladonna extract contains anticholinergic alkaloids that block acetylcholine receptors in the GI tract, reducing smooth muscle contractions and secretions. Phenobarbital enhances GABAergic inhibition in the CNS, providing calming effects.
Significant anticholinergic side effects including dry mouth, constipation, urinary retention, and blurred vision. May cause drowsiness and has addiction potential. Use cautiously in elderly, patients with glaucoma, BPH, or cardiac conditions. Avoid alcohol and operating machinery.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy