Benactyzine / Meprobamate
Benactyzine/Meprobamate is an older anxiolytic combination medication that pairs an anticholinergic agent with a carbamate sedative. It was historically prescribed for anxiety disorders and tension-related conditions, though its use has declined significantly in modern practice.
A historical combination anxiolytic medication containing an anticholinergic and sedative component, largely replaced by newer treatments.
Key facts at a glance
- RxNorm
- 690054
- Generic
- Benactyzine / Meprobamate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This combination was primarily used for managing anxiety, nervous tension, and related psychosomatic conditions. It may have been prescribed for anxiety associated with gastrointestinal symptoms due to the anticholinergic component.
Meprobamate produces sedation and anxiolytic effects through modulation of GABA-A receptor activity in the central nervous system. Benactyzine contributes anticholinergic properties, reducing parasympathetic nervous system activity and associated physical anxiety symptoms.
This medication has limited availability in most countries due to safety concerns with meprobamate, including dependence potential and overdose risk. It is not considered a first-line treatment in modern psychiatric practice. Patients should be aware of drowsiness risks and avoid operating machinery. This medication may interact with alcohol, other CNS depressants, and anticholinergic drugs. Discontinuation should be medically supervised due to potential withdrawal effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy