Diphenhydramine
Benadryl Itch Stopping is a topical antihistamine cream designed to provide temporary relief from itching and minor pain caused by skin irritations such as insect bites, poison ivy, sunburn, and other allergic skin reactions. The medication is applied directly to the affected skin area and works locally to soothe discomfort. This product is suitable for adults and children over 2 years old seeking fast-acting, external itch relief.
A topical cream that temporarily relieves itching and minor pain from skin irritations like insect bites, poison ivy, and sunburn.
Key facts at a glance
- RxNorm
- 607032
- Generic
- Benadryl Itch Stopping
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Benadryl Itch Stopping is used to temporarily relieve itching and pain associated with minor skin irritations, including insect bites, poison ivy/oak/sumac, sunburn, and other allergic skin reactions. It can also help with minor burns and irritations from soaps, detergents, cosmetics, or jewelry.
The active ingredient diphenhydramine is an antihistamine that works by blocking histamine, a substance in the body that causes allergic itching. When applied topically, it reduces itching at the site of application. Some formulations also contain zinc acetate, which provides additional skin-protectant properties.
For external use only—avoid contact with eyes, nose, and mouth. Do not apply to large areas of the body or broken/damaged skin. Should not be used on children under 2 years without medical advice. Stop use and consult a doctor if symptoms worsen or persist for more than 7 days. May cause drowsiness if absorbed in significant amounts through the skin.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy