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Bendeka is a prescription chemotherapy medication containing bendamustine that is used to treat certain types of cancer, specifically chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following prior treatment. It belongs to a class of drugs called alkylating agents and works by damaging cancer cell DNA, preventing their growth and causing cell death.
Bendeka is an IV chemotherapy drug used to treat CLL and certain types of non-Hodgkin lymphoma in adults.
Key facts at a glance
- RxNorm
- 1726098
- Generic
- Bendeka
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Bendeka is FDA-approved for the treatment of chronic lymphocytic leukemia (CLL) and for the treatment of patients with indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within 6 months of treatment with rituximab or a rituximab-containing regimen.
Bendeka contains bendamustine, an alkylating agent that works by binding to DNA and causing cross-linking of DNA strands. This prevents DNA replication and transcription, ultimately leading to cancer cell death. The medication targets rapidly dividing cells, including cancer cells.
Bendeka is administered as an intravenous infusion by a healthcare professional. Common side effects include myelosuppression (low blood cell counts), nausea, fatigue, and infusion reactions. Patients should be monitored for signs of infection due to lowered white blood cell counts. The medication may cause harm to a developing fetus and should not be used during pregnancy. Regular blood tests are required during treatment to monitor blood cell counts and organ function.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy