Bendroflumethiazide / Meprobamate
Bendroflumethiazide/meprobamate is a combination medication that pairs a thiazide diuretic with an anxiolytic agent. This older combination was historically used to treat hypertension, particularly in patients experiencing associated anxiety or tension.
A combination of a diuretic and tranquilizer used primarily for hypertension with anxiety symptoms.
Key facts at a glance
- RxNorm
- 1008681
- Generic
- Bendroflumethiazide / Meprobamate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
This medication has been used for hypertension (high blood pressure), particularly when associated with anxiety, tension, or mild depression. The combination was intended to address both the physical and emotional components of cardiovascular stress.
Bendroflumethiazide is a thiazide diuretic that reduces blood pressure by increasing water and sodium excretion, decreasing plasma volume, and reducing peripheral vascular resistance. Meprobamate is an anxiolytic that produces central nervous system depression, reducing anxiety and muscle tension.
This is an older medication combination that is rarely used in modern practice. Both components can cause drowsiness, and alcohol should be avoided. Thiazide diuretics may cause electrolyte imbalances, particularly low potassium. This medication may also cause dependence with prolonged use due to the meprobamate component.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy