Bendroflumethiazide / Reserpine
Bendroflumethiazide/Reserpine is a combination medication used to treat hypertension (high blood pressure). It combines a thiazide diuretic that helps reduce fluid volume with an agent that decreases sympathetic nervous system activity. This multi-pronged approach helps lower blood pressure in patients who don't respond adequately to single-agent therapy.
A combination antihypertensive medication pairing a diuretic with a sympathetic nervous system inhibitor for blood pressure control.
Key facts at a glance
- RxNorm
- 1007960
- Generic
- Bendroflumethiazide / Reserpine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to treat essential hypertension (high blood pressure). Typically considered when single-agent therapy is insufficient for blood pressure control.
Bendroflumethiazide is a thiazide diuretic that increases urinary excretion of sodium and water to reduce plasma volume, while Reserpine depletes norepinephrine from sympathetic nerve terminals to reduce sympathetic tone—both mechanisms result in lowered blood pressure.
May cause electrolyte imbalances (low potassium), drowsiness, or nasal congestion. May interact with other antihypertensives, digitalis, or lithium. Not typically used as first-line therapy in modern practice; alternative agents are often preferred due to side effect profile.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy