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Benphothiamine / Vitamin B6

Published: July 27, 2026Updated: August 28, 2026

Benphothiamine/Vitamin B6 is a combination supplement containing benphothiamine (a highly bioavailable form of thiamine/Vitamin B1) and pyridoxine (Vitamin B6). This combination is used to support nervous system function, treat or prevent B vitamin deficiencies, and manage certain types of peripheral neuropathy. It is commonly prescribed for patients with nerve-related conditions or those requiring nutritional support.

Quick summary

A combination supplement of benphothiamine and Vitamin B6 used to support nerve health and address vitamin B deficiencies.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008188
Generic
Benphothiamine / Vitamin B6
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used to treat and prevent Vitamin B1 and B6 deficiencies, support nervous system health in peripheral neuropathy, and provide nutritional support. Commonly prescribed for diabetic neuropathy, alcohol-related nerve damage, or general B vitamin insufficiency.

Benphothiamine is a fat-soluble derivative of thiamine that converts to active thiamine pyrophosphate (TPP), essential for nerve cell energy metabolism. Vitamin B6 serves as a cofactor in neurotransmitter synthesis and amino acid metabolism. Together they support optimal neurological function and nerve regeneration.

Should be taken as directed; excessive Vitamin B6 intake over prolonged periods may cause peripheral neuropathy. Benphothiamine is generally well-tolerated with minimal side effects. Patients with existing medical conditions or those taking other medications should consult their healthcare provider before use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy