Benzalkonium Chloride
Benzalkonium Chloride is a quaternary ammonium compound that acts as a cationic surfactant with broad-spectrum antimicrobial activity against bacteria, viruses, fungi, and certain parasites. It is primarily used as a preservative in ophthalmic solutions, nasal sprays, and other pharmaceutical formulations, as well as a topical antiseptic in various over-the-counter products.
Benzalkonium Chloride is a preservative and antiseptic agent used in eye drops, nasal sprays, and topical solutions to prevent microbial contamination and reduce infection risk.
Key facts at a glance
- RxNorm
- 1379
- Generic
- Benzalkonium Chloride
- Class
- pin-variant
- Brands
- Horseman's Dream Fung-A-Way, ReadyBath, DigiSan E Foam, Keystone, Zephiran, Safeguard Antibacterial Foaming, Pheneen, Releev Cold Sore, Mane 'N Tail Pro-Tect, Band-Aid Hurt-Free
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used as a preservative in multi-dose eye drops and nasal sprays to prevent bacterial contamination; topical antiseptic for minor skin wounds and infections; ingredient in throat lozenges and mouthwashes for oral antiseptic effects; sometimes used in pinworm treatments as a germicidal component.
Functions as a cationic surfactant that disrupts the lipid cell membranes of microorganisms, leading to cell lysis and death. Its amphiphilic structure allows it to penetrate and destroy bacterial, fungal, and viral envelopes.
May cause eye irritation or sensitivity reactions in some individuals; avoid contact with eyes during external application; not for use on deep puncture wounds or serious burns; may be toxic if ingested; some bacteria have developed resistance mechanisms.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy