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Benzalkonium / Chloroxylenol

Published: July 27, 2026Updated: August 28, 2026

Benzalkonium/chloroxylenol is a topical antiseptic combination used for skin disinfection and wound cleansing. The two active ingredients work together to provide broad-spectrum antimicrobial activity against bacteria, fungi, and certain viruses. This combination is commonly found in antiseptic solutions, wound cleansers, and some ophthalmic preparations.

Quick summary

A topical antiseptic combination for skin disinfection and wound care that works against a wide range of microorganisms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
2566800
Generic
Benzalkonium / Chloroxylenol
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for antiseptic skin cleansing, wound disinfection, minor cuts and abrasions, and as a preservative in certain eye drops and nasal sprays. May also be used for pre-operative skin preparation.

Benzalkonium chloride disrupts microbial cell membranes as a quaternary ammonium compound, while chloroxylenol denatures proteins and disrupts cell walls as a phenolic antiseptic. Together they provide synergistic broad-spectrum antimicrobial activity.

For topical use only; avoid contact with eyes unless specifically formulated for ophthalmic use. Should not be used on large areas of burned or damaged skin. Some individuals may experience skin irritation or allergic reactions. Not for internal use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy