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Benzalkonium / Chloroxylenol / Hydrocortisone

Published: July 27, 2026Updated: August 28, 2026

This multi-ingredient topical medication combines two antiseptic agents (benzalkonium chloride and chloroxylenol) with a mild topical corticosteroid (hydrocortisone) to address inflammatory skin conditions that may involve or risk bacterial contamination. The antiseptics help reduce microbial growth on the skin while hydrocortisone works to decrease inflammation, redness, and itching. This medication is typically prescribed for inflammatory dermatoses complicated by or at risk of secondary bacterial infection, such as certain cases of eczema or dermatitis.

Quick summary

A topical combination of antiseptics and a corticosteroid used to treat inflamed skin conditions with potential or actual secondary bacterial infection.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008913
Generic
Benzalkonium / Chloroxylenol / Hydrocortisone
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Topical treatment of inflammatory skin disorders where there is a risk of or existing secondary bacterial infection, such as infected eczema, dermatitis, or other inflammatory dermatoses requiring both anti-inflammatory and antimicrobial action.

Hydrocortisone provides anti-inflammatory and anti-itch effects by suppressing local immune responses and reducing inflammatory mediators. Benzalkonium chloride and chloroxylenol act as antiseptic agents that help control bacterial growth on the skin surface, preventing or treating associated infections.

For external use only on intact skin. Avoid application to large body areas, broken skin, or under occlusive dressings for prolonged periods due to increased systemic absorption risk, particularly in children. Use caution near eyes, mouth, and mucous membranes. Should not be used on viral or fungal infections without appropriate antimicrobial coverage.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy