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Benzalkonium / Didecyldimethylammonium Chloride / Polyaminopropyl Biguanide

Published: July 27, 2026Updated: August 28, 2026

This is a topical antiseptic combination product containing quaternary ammonium compounds and a biguanide derivative. It is commonly used for skin disinfection, wound cleansing, and as a preservative in ophthalmic solutions. The combination provides broad-spectrum antimicrobial activity against bacteria and some fungi.

Quick summary

A topical antiseptic combination used for skin disinfection and wound care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
2360646
Generic
Benzalkonium / Didecyldimethylammonium Chloride / Polyaminopropyl Biguanide
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for antiseptic skin cleansing, wound disinfection, and as a preservative in certain eye care products. May be found in contact lens solutions and topical disinfectants.

The quaternary ammonium compounds (benzalkonium and didecyldimethylammonium) disrupt microbial cell membranes, while polyaminopropyl biguanide damages bacterial cell walls and membranes. Together they provide broad-spectrum antimicrobial activity.

For external use only. Avoid contact with eyes unless specifically formulated for ophthalmic use. Some ingredients may cause skin irritation in sensitive individuals. Not typically used for deep tissue infections or as a primary treatment for infected wounds requiring systemic antibiotics. Should not be ingested.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy