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Benzalkonium / Idoxuridine / Lidocaine

Published: July 27, 2026Updated: August 28, 2026

This medication is a combination product used for treating herpes simplex infections of the eye (keratitis). It combines an antiviral agent (idoxuridine) to fight the viral infection, a local anesthetic (lidocaine) to relieve associated pain and discomfort, and an antiseptic component (benzalkonium) that helps prevent secondary bacterial infections. This ophthalmic preparation is typically prescribed when patients experience both viral eye infection symptoms and significant discomfort.

Quick summary

An ophthalmic combination medication used to treat herpes simplex eye infections by combining antiviral, anesthetic, and antiseptic properties.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008470
Generic
Benzalkonium / Idoxuridine / Lidocaine
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of herpes simplex keratitis (viral eye infection caused by herpes simplex virus), particularly when associated with significant eye pain and discomfort. May also help prevent secondary bacterial infections of the cornea.

Idoxuridine interferes with viral DNA synthesis, inhibiting herpes simplex virus replication. Lidocaine provides localized anesthetic effect by blocking sodium channels, reducing pain signals in the affected eye tissue. Benzalkonium chloride acts as an antiseptic agent and preservative in the formulation.

For ophthalmic use only. Apply exactly as directed by your healthcare provider. Do not touch the dropper tip to any surface including the eye to avoid contamination. Temporary blurred vision may occur after application. Treatment duration is typically limited due to potential toxicity with prolonged use. Inform your doctor if symptoms do not improve within a few days or if they worsen.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy