Benzalkonium / Pramoxine
Benzalkonium/Pramoxine is a topical combination medication used primarily for relief of pain, itching, and discomfort associated with hemorrhoids and other anal or perianal conditions. It combines an antiseptic (benzalkonium) with a local anesthetic (pramoxine) to both prevent infection and provide numbing relief.
Topical hemorrhoid treatment combining antiseptic and anesthetic properties for pain and itching relief.
Key facts at a glance
- RxNorm
- 1008277
- Generic
- Benzalkonium / Pramoxine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves pain, itching, and discomfort from hemorrhoids; also used for anal fissures, proctitis, and perianal irritation. Available as creams, wipes, and suppositories typically applied rectally or perianally.
Benzalkonium chloride is a quaternary ammonium antiseptic that kills bacteria and some fungi on contact. Pramoxine is a local anesthetic that blocks nerve signals in the skin to produce numbness and relieve itching. Together they address both infection prevention and symptom relief.
For external use only or as directed for internal rectal use. Avoid contact with eyes. Not recommended for prolonged daily use without medical advice. Discontinue if irritation, rash, or worsening symptoms occur. Inform your doctor if pregnant or breastfeeding before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy