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Benzalkonium / Tyloxapol

Published: July 27, 2026Updated: August 28, 2026

Benzalkonium/Tyloxapol is an ophthalmic medication combination used primarily in eye drop formulations. Benzalkonium chloride serves as a preservative to maintain sterility, while Tyloxapol acts as a surfactant to help disperse active ingredients and improve contact with the eye surface. This combination is commonly found in lubricating eye drops and artificial tear preparations for dry eye relief.

Quick summary

An ophthalmic eye drop formulation combining a preservative with a surfactant to relieve dry eyes and maintain eye comfort.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1049378
Generic
Benzalkonium / Tyloxapol
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for temporary relief of dry, irritated eyes; artificial tear supplementation; and general eye lubrication. Commonly formulated for conditions involving insufficient tear production or poor tear film stability.

Tyloxapol acts as a non-ionic surfactant to lower surface tension and improve spreading of the solution across the corneal surface. Benzalkonium chloride preserves the formulation by preventing microbial contamination, extending the product's shelf life.

For ophthalmic use only; avoid touching the dropper tip to any surface to prevent contamination. Contact lens compatibility varies by formulation—consult with an eye care professional. Discontinue use and seek medical attention if eye pain, vision changes, or persistent irritation occurs. Not a replacement for medical treatment of underlying eye conditions.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy