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Benzalkonium / Urea

Published: July 27, 2026Updated: August 28, 2026

Benzalkonium/Urea is a topical combination medication that pairs an antiseptic agent with a moisturizing compound. Benzalkonium chloride provides antimicrobial protection while urea acts as a humectant and keratolytic to help hydrate skin and soften thickened skin. This combination is typically used for various dermatological conditions involving dry, rough, or compromised skin.

Quick summary

A topical antiseptic-moisturizer combination used for skin conditions requiring both antimicrobial protection and hydration.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1291283
Generic
Benzalkonium / Urea
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for management of dry, scaly skin conditions such as xerosis, ichthyosis, and rough skin. May also be used on skin areas requiring antiseptic protection alongside moisturization.

Benzalkonium chloride is a quaternary ammonium compound that disrupts microbial cell membranes, providing antibacterial activity. Urea is a natural moisturizing factor that attracts water to the skin and helps break down keratin, softening and smoothing the skin barrier.

For external use only. Avoid contact with eyes and mucous membranes. Some individuals may experience skin irritation or sensitivity to benzalkonium chloride. Discontinue use if severe irritation or allergic reaction occurs. Consult a healthcare provider before use on broken or extensively damaged skin.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy