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Benzethonium / Polidocanol / Urea

Published: July 27, 2026Updated: August 28, 2026

This multi-ingredient topical medication combines antiseptic, sclerosing, and keratolytic properties. Benzethonium provides antimicrobial protection while polidocanol acts as a local anesthetic and sclerosing agent, and urea helps moisturize and soften thickened skin. It is typically used for superficial skin conditions requiring cleansing, pain relief, and skin softening effects.

Quick summary

Topical medication combining antiseptic, anesthetic, and moisturizing ingredients for various skin conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1007690
Generic
Benzethonium / Polidocanol / Urea
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used for superficial skin conditions requiring antiseptic cleansing, pain relief, and softening of thickened or calloused skin, such as hemorrhoids, fissures, or localized skin irritations.

Benzethonium provides antimicrobial activity, polidocanol acts as a local anesthetic and sclerosing agent to reduce discomfort and promote healing of vascular tissue, and urea hydrates and softens skin by enhancing moisture retention and breaking down dead skin cells.

For topical/external use only. Avoid contact with eyes and mucous membranes. Discontinue use if irritation or allergic reaction occurs. Not recommended for use on large areas of broken skin. Consult healthcare provider before use during pregnancy or breastfeeding.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy