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Benzhydrocodone Hydrochloride

Published: July 26, 2026Updated: August 27, 2026

Benzhydrocodone Hydrochloride is an opioid analgesic combined with acetaminophen, used for the short-term management of acute pain severe enough to require opioid treatment. As a prodrug, it converts to hydrocodone in the body, which binds to opioid receptors in the central nervous system to reduce pain perception. This medication is typically prescribed when other pain management options are insufficient.

Quick summary

An opioid pain medication used for short-term treatment of moderate to severe acute pain.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
2122776
Generic
Benzhydrocodone Hydrochloride
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Short-term management of acute pain severe enough to require opioid treatment, typically for periods of up to 14 days.

Benzhydrocodone is a prodrug that converts to hydrocodone in the body, which binds to mu-opioid receptors in the brain and spinal cord to alter pain perception and produce analgesic effects.

Contains an acetaminophen component, which carries risk of liver damage at high doses. Has significant potential for dependence, addiction, and abuse. Should be used with caution and typically reserved for situations where alternative pain treatments are inadequate. Always follow prescribing physician's instructions regarding dosing and duration.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy