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Benzocaine / Bismuth Subgallate / Zinc Oxide

Published: July 27, 2026Updated: August 28, 2026

This medication combines three active ingredients for topical application: a local anesthetic (benzocaine) to relieve pain and discomfort, bismuth subgallate for its protective and astringent properties, and zinc oxide to provide a protective barrier. This combination is commonly used to temporarily relieve pain, itching, and discomfort associated with minor skin irritations and anorectal conditions.

Quick summary

A topical combination product providing pain relief and protective barrier effects for minor skin and anorectal irritations.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008433
Generic
Benzocaine / Bismuth Subgallate / Zinc Oxide
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Temporarily relieves pain, itching, burning, and discomfort associated with minor skin irritations, hemorrhoids, and anorectal conditions. May also be used for minor cuts, scrapes, or skin irritation requiring local anesthesia and protection.

Benzocaine provides local anesthetic effects by blocking nerve signals in the applied area. Bismuth subgallate acts as an astringent with protective properties. Zinc oxide forms a protective barrier on the skin while providing mild astringent effects. Together, they address both symptom relief and protection.

For external use only. Avoid contact with eyes. Do not use on large areas of the body, broken skin, or for prolonged periods without medical advice. Rare but serious methemoglobinemia has been reported with benzocaine use. Discontinue and seek medical attention if symptoms worsen or do not improve within 7 days. Keep out of reach of children.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy