Benzocaine / Capsaicin / Menthol / Methyl Salicylate
This topical medication combines four active ingredients that work together to relieve pain and itching. The formulation includes a local anesthetic (benzocaine) along with counter-irritants (capsaicin, menthol, methyl salicylate) that create warming and cooling sensations to override pain signals. It is commonly used for temporary relief of minor muscle aches, joint pain, and skin irritations such as insect bites or itching.
A topical pain-relieving combination used for temporary relief of minor muscle and joint pain, as well as skin itching and irritation.
Key facts at a glance
- RxNorm
- 1008787
- Generic
- Benzocaine / Capsaicin / Menthol / Methyl Salicylate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of minor muscle and joint pain associated with arthritis, strains, sprains, and backaches. Also used for relief of itching, skin irritation, and discomfort from insect bites, minor burns, or scrapes.
The combination works through multiple mechanisms: benzocaine provides local numbing by blocking nerve signals, capsaicin depletes substance P to reduce pain perception and creates a warming sensation, menthol triggers cold receptors to create a cooling distraction effect, and methyl salicylate provides anti-inflammatory and analgesic effects similar to topical aspirin.
For external use only—do not apply to broken skin, wounds, or mucous membranes. Avoid contact with eyes and sensitive areas. Do not bandage tightly or use with heating pads, as this may increase absorption and risk of side effects. Discontinue use if severe irritation, rash, or allergic reaction occurs. Keep out of reach of children. Wash hands thoroughly after application.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy