Benzocaine / Ephedrine
Benzocaine/Ephedrine is a topical combination medication used to temporarily relieve nasal congestion and discomfort associated with sinus pressure. Benzocaine provides local anesthetic effects to reduce pain, while ephedrine acts as a decongestant to shrink swollen nasal passages. This medication is commonly used before medical procedures or to manage symptoms of colds, allergies, or sinus congestion.
A topical nasal decongestant and anesthetic combination that temporarily relieves nasal congestion and sinus discomfort.
Key facts at a glance
- RxNorm
- 1008566
- Generic
- Benzocaine / Ephedrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion due to common cold, hay fever, or upper respiratory allergies. May also be used as a local anesthetic during nasal or upper airway procedures.
Benzocaine blocks nerve signals in the applied area to provide numbing effect, while ephedrine constricts blood vessels in the nasal passages to reduce swelling and congestion.
Should not be used for more than 3-5 days due to risk of rebound congestion. Avoid use in patients with heart disease, high blood pressure, thyroid disease, diabetes, or difficulty urinating. Not recommended for children unless specifically directed by a healthcare provider. Discontinue use and seek medical attention if symptoms worsen or no improvement occurs.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy