Benzocaine / Phenylephrine
Benzocaine/Phenylephrine is a topical combination medication used to temporarily relieve nasal and sinus congestion along with associated discomfort. The two ingredients work together—benzocaine provides local anesthetic relief while phenylephrine acts as a decongestant to reduce swelling in the nasal passages. This medication is commonly found in nasal sprays and topical solutions for short-term relief of stuffy nose symptoms.
Topical decongestant and anesthetic combination for temporary relief of nasal congestion.
Key facts at a glance
- RxNorm
- 1008329
- Generic
- Benzocaine / Phenylephrine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporarily relieves nasal congestion, sinus congestion, and associated facial pressure or discomfort due to colds, allergies, or sinusitis. Often used before medical procedures involving the nasal passages.
Benzocaine is a local anesthetic that numbs the tissues it contacts, providing temporary pain relief. Phenylephrine is an alpha-1 adrenergic agonist that constricts blood vessels in the nasal passages, reducing swelling and congestion.
For topical intranasal use only—do not ingest. Should not be used for more than 3 days consecutively due to risk of rebound congestion. Avoid use in children unless specifically directed by a healthcare provider. May interact with certain medications including MAO inhibitors and blood pressure medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy