Benzocaine / Phenylpropanolamine
Benzocaine/Phenylpropanolamine is a combination medication that provides topical anesthetic and decongestant effects. Benzocaine temporarily numbs sore or irritated throat tissue, while phenylpropanolamine reduces nasal and sinus congestion by constricting blood vessels. This medication is commonly used for temporary relief of cold, flu, or allergy symptoms affecting both the throat and nasal passages.
A dual-action medication combining a topical anesthetic with a decongestant for symptomatic relief of sore throat and nasal congestion.
Key facts at a glance
- RxNorm
- 1006912
- Generic
- Benzocaine / Phenylpropanolamine
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of sore throat pain, throat irritation, and nasal/sinus congestion associated with common cold, flu, or upper respiratory allergies
Benzocaine blocks sodium channels in nerve endings, preventing pain signal transmission for topical numbing. Phenylpropanolamine stimulates alpha-adrenergic receptors, causing vasoconstriction that reduces swelling in nasal and sinus passages.
For short-term use only (typically 2-3 days). Avoid in children unless directed by a physician. Contraindicated in patients with cardiovascular disease, hypertension, thyroid disorders, or glaucoma. May interact with MAO inhibitors and other sympathomimetic drugs. Discontinue and consult a doctor if symptoms persist beyond 7 days.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy