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Benzocaine / Zirconium Oxide

Published: July 27, 2026Updated: August 28, 2026

Benzocaine/Zirconium Oxide is a topical oral medication combining a local anesthetic with an abrasive agent. This multi-ingredient preparation is primarily used in dental settings for pain relief during procedures and for treating tooth sensitivity. The combination allows for both numbing of oral tissues and mechanical polishing or desensitizing effects.

Quick summary

A topical oral medication combining an anesthetic with an abrasive, used for dental pain relief and tooth sensitivity.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1007578
Generic
Benzocaine / Zirconium Oxide
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

This medication is used for temporary relief of oral pain and tooth sensitivity, commonly applied during dental cleanings, polishing, or minor dental procedures. It may also be used for symptomatic relief of mouth sores or gum irritation.

Benzocaine works by blocking nerve signals in the treated area, creating a temporary numbing effect. Zirconium oxide acts as a fine abrasive agent that helps smooth tooth surfaces and may assist in occluding dentinal tubules to reduce sensitivity.

For topical oral use only. Avoid using on large areas or broken skin. Do not exceed recommended application frequency. Rare but serious side effects including methemoglobinemia have been reported with topical benzocaine, particularly in children. Discontinue use if rash, swelling, or breathing difficulties occur. Consult a dentist or healthcare provider before use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy