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Benzoyl Peroxide / Clindamycin

Published: July 27, 2026Updated: August 28, 2026

Benzoyl Peroxide/Clindamycin is a topical combination medication used to treat acne vulgaris. It combines clindamycin, an antibiotic that reduces bacteria, with benzoyl peroxide, which helps reduce oil and unclog pores. This dual-action approach makes it effective for moderate acne when single-ingredient treatments haven't worked.

Quick summary

Topical combination medication for treating acne by reducing bacteria and unclogging pores.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
646781
Generic
Benzoyl Peroxide / Clindamycin
Class
multi-ingredient
Brands
Neuac, Onexton, Acanya
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Primarily used to treat acne vulgaris (common acne) on the face, chest, or back. Often prescribed when over-the-counter acne products have been ineffective, particularly for inflammatory acne with papules and pustules.

Clindamycin is an antibiotic that inhibits the growth of acne-causing bacteria (Cutibacterium acnes), while benzoyl peroxide works as a keratolytic agent that helps shed dead skin cells and reduces oil production. Together, they provide complementary mechanisms to reduce acne lesions.

May cause skin dryness, irritation, or peeling during initial use. Avoid excessive sun exposure and use sunscreen. Bleaching of hair and colored fabrics may occur with benzoyl peroxide. Complete the full course as prescribed even if improvement is seen earlier.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy