Benzoyl Peroxide / Colloid Sulfur
Benzoyl Peroxide/Colloid Sulfur is a topical combination medication used to treat acne and related skin conditions. Benzoyl peroxide works by reducing acne-causing bacteria on the skin, while colloid sulfur provides additional antibacterial and keratolytic (skin-softening) effects. This combination is typically prescribed when single-ingredient acne treatments have not been effective enough.
A topical acne treatment combining two active ingredients for enhanced effectiveness against pimples and skin blemishes.
Key facts at a glance
- RxNorm
- 1008966
- Generic
- Benzoyl Peroxide / Colloid Sulfur
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for the treatment of acne vulgaris (common acne), including inflammatory acne (papules, pustules) and non-inflammatory acne (blackheads, whiteheads). May also be used for seborrheic dermatitis and rosacea in some cases.
Benzoyl peroxide releases oxygen to kill acne-causing bacteria (P. acnes) and may reduce oil production. Colloid sulfur has antibacterial, antifungal, and keratolytic properties that help break down dead skin cells and reduce clogged pores. Together, they provide complementary mechanisms for clearer skin.
Apply only to affected areas as directed—usually once daily initially, increasing to 2-3 times daily as tolerated. May cause dryness, redness, peeling, and skin irritation, especially when starting treatment. Can bleach hair and fabrics. Avoid sun exposure and use sunscreen, as sensitivity to sunlight may increase. Not recommended during pregnancy without medical consultation. Keep away from eyes, mouth, and mucous membranes.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy