Benzoyl Peroxide / Hydrocortisone
Benzoyl Peroxide/Hydrocortisone is a topical combination medication used primarily for treating inflammatory acne. Benzoyl peroxide works as an antibacterial agent to reduce acne-causing bacteria on the skin, while hydrocortisone provides anti-inflammatory effects to reduce redness, swelling, and discomfort. This combination is particularly useful for inflammatory acne lesions such as papules and pustules.
A topical acne treatment combining an antibacterial agent with a mild anti-inflammatory corticosteroid.
Key facts at a glance
- RxNorm
- 392454
- Generic
- Benzoyl Peroxide / Hydrocortisone
- Class
- multi-ingredient
- Brands
- Vanoxide-HC
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of inflammatory acne vulgaris, including papules, pustules, and mild to moderate acne. May also be used for other inflammatory skin conditions as directed by a healthcare provider.
Benzoyl peroxide releases oxygen to kill acne-causing bacteria (Propionibacterium acnes) and helps reduce oil buildup, while hydrocortisone is a mild corticosteroid that reduces inflammation, itching, and redness associated with acne lesions.
For external use only. May bleach hair or fabrics. May cause skin dryness, irritation, or peeling initially. Avoid contact with eyes, mouth, and mucous membranes. Not recommended for use during pregnancy without medical advice. Consult a healthcare provider if no improvement occurs after several weeks of use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy