Benzoyl Peroxide / Sulfur
Benzoyl Peroxide/Sulfur is a topical combination medication used to treat acne vulgaris. Benzoyl peroxide works as a keratolytic agent and reduces acne-causing bacteria on the skin, while sulfur has antimicrobial and exfoliating properties that help clear pores. Together, they provide a dual-action approach to reducing acne lesions, making this combination particularly useful for mild to moderate inflammatory and non-inflammatory acne.
A topical acne treatment combining two keratolytic and antimicrobial agents to reduce comedones and inflammatory lesions.
Key facts at a glance
- RxNorm
- 392483
- Generic
- Benzoyl Peroxide / Sulfur
- Class
- multi-ingredient
- Brands
- NuOx
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Mild to moderate acne vulgaris, including blackheads, whiteheads, and inflammatory lesions such as papules and pustules. Often considered for patients who need gentle yet effective acne management.
Benzoyl peroxide releases oxygen to inhibit acne-causing bacteria (C. acnes) and promotes skin cell turnover, while sulfur acts as a keratolytic to help shed dead skin cells and has inherent antimicrobial properties. The combination may enhance efficacy compared to either agent alone.
May cause skin dryness, redness, peeling, or irritation, especially during initial treatment. Can bleach hair, towels, and clothing. Sun exposure should be minimized as sensitivity may increase. Typically applied once daily initially, then adjusted based on tolerance. Avoid contact with eyes, mouth, and mucous membranes.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy