Benzydamine
Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) primarily used as a topical treatment for painful inflammatory conditions of the mouth and throat. It is commonly prescribed or recommended for conditions like sore throat and mouth ulcers.
Benzydamine is a topical NSAID that provides pain relief and reduces inflammation in the mouth and throat.
Key facts at a glance
- ATC
- A01AD02
- RxNorm
- 1425
- Generic
- Benzydamine
- Class
- atc-a01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral, topical
- Forms
- spray, cream
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
7 groupspregnancy
first trimesteravoid if possible
use only if benefits outweigh potential risks, avoid prolonged use
regular prenatal care
Use with caution and monitor for adverse effects.
pregnancy
third trimesterdo not use
avoid use in third trimester due to risk of premature closure of ductus arteriosus and prolonged labor
fetal monitoring if exposed
Use of this medication in this population requires careful consideration of risks and benefits.
lactation
breastfeedinguse with caution
minimal systemic absorption when used topically, but caution advised
monitor infant for adverse effects
Use with caution and monitor for adverse effects.
pediatric_age
children under 12age-specific dosing required
not recommended for children under 12 years due to limited safety data
monitor for adverse reactions
Use with caution and monitor for adverse effects.
geriatric
elderlyreduce frequency if needed
use with caution due to increased susceptibility to adverse effects
monitor renal function and for gastrointestinal effects
Use with caution and monitor for adverse effects.
renal_impairment
mild to moderateno adjustment typically needed for topical use
use with caution, minimal systemic absorption expected
monitor renal function periodically
Use with caution and monitor for adverse effects.
hepatic_impairment
mild to moderateno adjustment typically needed for topical use
use with caution, monitor for adverse effects
periodic liver function monitoring
Use with caution and monitor for adverse effects.
Statistics and clinical data
Drug class
Drug class information
First marketed
First introduction to market
Common uses
Common therapeutic uses
Common formulations
Available dosage forms
Benzydamine is used to treat inflammatory and painful conditions of the oral cavity and throat, including sore throat, pharyngitis, tonsillitis, gingivitis, stomatitis, and mouth ulcers. It is also available as a topical cream for musculoskeletal conditions such as sprains and strains.
Benzydamine works by inhibiting the production of prostaglandins, which are substances involved in inflammation and pain. It also has local anesthetic and mild antimicrobial properties, providing multi-faceted relief when applied directly to the affected area.
Benzydamine is generally well-tolerated when used topically as directed. Common side effects may include local burning or stinging sensation. It should not be swallowed in large amounts when used as a mouthwash. As with all medications, patients should follow package directions or medical advice regarding proper use and duration of treatment.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy